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CSIRO Postdoctoral Fellowship in Predictive modelling of human gut microbiome


CSIRO Early Research Career (CERC) Postdoctoral Fellowships provide opportunities to scientists and engineers who have completed their doctorate and have less than three years of relevant postdoctoral work experience. These fellowships aim to develop the next generation of future leaders of the innovation system.

The position will be part of the Microbiomes for One Systems Health – Future Science Platform (FSP). CSIRO FSPs address new scientific challenges for Australia.

The Microbiome FSP is developing new understanding of microbiome connectivity across the environment to human continuum and how system perturbations impact on microbiome functionality, diversity and systems health.  A key objective is to capture greater benefit from microbiome interactions through more informative and predictive frameworks for functionality and by targeted interventions. Capacity to directly manipulate microbiomes across hosts and environments will provide new opportunities for bio-based solutions to be developed and applied to improve host and environmental health and for increased benefit to plants, animals and humans.

The portfolio of research within the Microbiome FSP is focussed around new science that address; systems connectivity, predictive frameworks and deliberate Interventions through the application of multi-omic tools to analyse point and system level change and associated measures of functionality both within and across interconnected biomes. This includes integration and analysis of multi-layered data and use of empirical and/or statistical modelling.  The science portfolio of the FSP spans multiple CSIRO Business Units that address key focal areas that include; i) Environment, Soil & Plant Health, ii) Food Chain & Production ii) Diet, Gut and Health and iv) Optimized Industry & Urban Processes.

This is an exciting opportunity for a Postdoctoral fellow to join a multidisciplinary team in the Nutrition and Health program to utilise their knowledge in microbiology and skills in bioinformatics and biostatistics to define the critical elements of the human gut microbiome (both microbial populations and their metabolic products) that are important for maintaining health (and/or predicting disease states), and their key influences, to construct a working model (or models) of the ideal human gut microbiome. This includes understanding the influence of microbes and their products from other domains such as plants, soils and animals, as well as foods. The activity is expected to lead to impact in the long-term for Australian and global communities by reducing the burden of disease through the development of better markers of health and disease, to improve our ability to inform the health state of an individual and susceptibility to disease will lead to better diagnostic methods and products. The Fellow will be exposed to a range of cutting-edge technologies, from organoid technologies to physics-based computational modelling.
Further information:

Your duties will include:

  • Process and analyse large -omics datasets (in-house and public domain) specific to microbial studies, metagenomics, metabolomics, and NGS data
  • Assist with the design and execution of experiments to enable generation of meaningful data to define the keystone species of the human gut microbiome responsible for a healthy gut
  • Participate in collaborative research with scientists in the Microbiomes for Ones Systems Health – Future Science Platform
  • Carry out innovative, impactful research of strategic importance to CSIRO that will, where possible, lead to novel and important scientific outcomes.
  • Recognise and exploit opportunities for innovation and the generation of new theoretical perspectives, and progress opportunities for the further development or creation of new lines of research
  • Utilise design thinking methodology to plan and prepare research proposals, and apply impact methodology to research projects
  • Carry out research investigations requiring originality, creativity and innovation

If you meet the majority of these requirements, please consider applying.

Location: North Ryde, NSW (relocating to Westmead Innovation Quarter in 2022)

Salary: AU$88k – AU$96k plus up to 15.4% superannuation

Tenure: Specified term of 3 years

Reference: 76414

To be considered you will need:

  • A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as microbiology, bioinformatics and statistics or similar. Please note: To be eligible for this role you must have no more than 3 years (or full-time equivalent) of postdoctoral research experience.
  • Demonstrated understanding of the human gut microbiome and human intestinal biology
  • Demonstrated experience with analysis of large datasets, including metagenomics, or metabolomics or bioinformatic and statistical analysis, to obtain meaningful health or clinical outcomes.
  • Technical knowledge or experience in analytical techniques such as mass spectrometry and microbial sequencing/NGS.
  • The ability and desire to work effectively as part of a multi-disciplinary, potentially regionally dispersed research team in NSW, SA and Victoria, plus the motivation and discipline to carry out autonomous research.
  • High level written and oral communication skills with the ability to represent the research team effectively internally and externally, including the presentation of research outcomes at national and international conferences.
Fully Funded Scholarships for International Students to Work and Study Abroad

For full details about this role please view the Position Description


To be eligible you must be an Australian/New Zealand Citizen, Australian Permanent Resident or Australian temporary resident currently residing in Australia (visa sponsorship may be provided to eligible onshore candidates) and be able to commence employment by December 2021/January 2022.

The successful applicant will be required to obtain and provide a National Police Check or equivalent. Additional integrity checks may be required for specific roles which require security clearance for working with children, Australian Government cybersecurity requirements or other identified security roles.

Flexible Working Arrangements

We work flexibly at CSIRO, offering a range of options for how, when and where you work.

Diversity and Inclusion

We are working hard to recruit people representing the diversity across our society, and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish.


At CSIRO Australia’s national science agency, we solve the greatest challenges through innovative science and technology. We put the safety and wellbeing of our people above all else and earn trust everywhere because we only deal in facts. We collaborate widely and generously and deliver solutions with real impact.

Join us and start creating tomorrow today!

How to Apply

Please apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.

Applications Close

20 September 2021, 11:00pm AEST

Apply now »

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